Dr. Samuel Ko Offers an Alternative to Treat Mental Illnesses

How does IV ketamine work for depression, anxiety, and PTSD?

Ketamine works on the NMDA (N-methyl-D-aspartate) receptor to block the glutamate neurotransmitter. Scientific studies show that ketamine improves the health of the neurons (brain cells) by increasing the connection between the neurons and improving the brain’s ability to adapt (aka neuroplasticity). Furthermore, ketamine decreases activity in the brain’s default mode network (DMN), which is more active in those with depression, anxiety, and PTSD.

What side effects does IV ketamine have?

Ketamine is a dissociative anesthetic medication, meaning some people will have an out-of-body experience and/or psychedelic experience. It can also cause nausea, vomiting, headaches, and fatigue afterwards. In some cases, it can raise blood pressure and pulse. Trained medical professionals will monitor all of your vital signs closely and will be readily available at your side.